Computational Cancer Genomics

Genome sequencing projects and new high-throughput technologies are producing large amounts of biological data that are potentially relevant to cancer. Our group contributes to the analysis of these data by developing new methods and database resources related to genome structure and gene regulation. In addition, we apply computational approaches to specific questions about transcriptional regulation. In particular, we try to identify and characterize transcriptional control mechanisms distorted in cancer cells by analyzing public data.